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The ARC houses several neural populations that are critical for regulating appetite and energy balance, including hunger-promoting agouti-related peptide–expressing (AgRP-expressing) neurons (65–69), satiety-inducing proopiomelanocortin-expressing (POMC-expressing) neurons (70, 71), and multiple other populations of appetite- and metabolism-regulating neurons (72–75)
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Brain insulin resistance in type 2 diabetes and Alzheimer disease: Concepts and conundrums
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